0451U Medicare Reimbursement Rate (2025)
Current CMS pricing and breakdown for Onc mm lc-ms/ms pep ion quan.
National Average Payment
National Medicare Payment
$43.43
This fee schedule does not publish separate facility and non-facility rates for this code.
Effective Q3 2025
ℹ️ Good to Know
This item has a standard price nationwide. Your local rate will likely match the amount shown above.
Historical Medicare Reimbursement
| Quarter | National Medicare Payment | YoY % Change |
|---|---|---|
| 2026 Q3 | — | — |
| 2026 Q2 | — | — |
| 2026 Q1 | — | — |
| 2025 Q4 | — | — |
| 2025 Q3 | $43.43 | — |
| 2025 Q2 | $43.43 | — |
| 2025 Q1 | $43.43 | — |
Code Description
Testing paraproteins in blood, results compared to baseline results to
Reimbursement Summary
CPT code 0451U (Testing paraproteins in blood, results compared to baseline results to) had a 2025 Medicare non-facility reimbursement rate of $43.43.
The 2025 National Medicare reimbursement for 0451U is $43.43. This item is paid at a standard national rate, so local variation is typically minimal.
Description: Testing paraproteins in blood, results compared to baseline results to. Payment policies and coverage rules can still vary by setting and claim details, so confirm final guidance through CMS when needed.
Q3 2025 Breakdown
| Component | Office (Non-Fac) | Facility (Hosp) |
|---|---|---|
| Work RVU | ||
| Practice Expense (PE) | ||
| Malpractice (MP) | ||
| Total RVUs | 0.00 | 0.00 |
Are you being paid correctly for this code?
Compare a payment against the Medicare benchmark for this code.
Medicare rates are used as a benchmark only. Actual payer contracts, modifiers, place of service, units, and billing rules may affect reimbursement. This tool is for educational and operational review purposes, not legal or billing advice.
Facility vs. Non-Facility (Office) Payment
Facility vs. non-facility pricing most commonly applies to physician services paid under the RVU-based Physician Fee Schedule. For 0451U (Clinical Laboratory Test), the payment methodology may not include both facility and non-facility rates.
Learn How This Reimbursement Is Calculated
Medicare reimbursement is determined by RVUs, geographic adjustments, and the annual conversion factor.
Frequently Asked Questions
What is the 2025 Medicare rate for 0451U?
The 2025 National Average Medicare reimbursement rate for 0451U (Clinical Laboratory Test) is $43.43. This rate is effective as of January 1, 2025.
What is the description for code 0451U?
Testing paraproteins in blood, results compared to baseline results to
Why do facility and non-facility payments differ for 0451U?
Facility vs. non-facility differences usually apply to RVU-based physician services. 0451U may not use both facility and non-facility pricing depending on its payment methodology.
How can I find my local Medicare rate for 0451U?
Use MedFeeSchedule's Medicare Physician Fee Schedule Lookup Tool on the homepage to estimate your locality-adjusted reimbursement. Medicare payment can vary based on geographic adjustments (GPCI), place of service, and claim specifics.
Is 0451U covered by Medicare?
Coverage depends on medical necessity, setting, and Medicare policy. Some codes may be bundled, contractor-priced, or restricted. Verify final coverage guidance through CMS or your local MAC when applicable.
