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Clinical Laboratory Test

0645U Medicare Reimbursement Rate (2026)

Current CMS pricing and breakdown for Onc leukemia mrd based dpcr.

HCPCS Code 0645UNo National Rate

National Average Payment

Non-Facility (Private Office) Rate

Varies
A national base rate is not currently published.

0645U Reimbursement Rate History

QuarterQ2 2025Q3 2025Q4 2025Q1 2026Q2 2026Q3 2026
National Average Payment

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Code Description

Oncology (leukemia), minimal residual disease (mrd) detection for rearrangements, based on digital pcr, blood or bone marrow, reported as not detected or detected with estimated abundance

Reimbursement Summary

CPT code 0645U (Oncology (leukemia), minimal residual disease (mrd) detection for rearrangements, based on digital pcr, blood or bone marrow, reported as not detected or detected with estimated abundance) does not currently have a published national facility or non-facility reimbursement rate in 2026.

0645U is a CPT code in the category “Clinical Laboratory Test.” Medicare does not publish a single national payment amount for this code in 2026 (No National Rate). A national base rate is not currently published.

To estimate a local payment amount when available, use MedFeeSchedule's Medicare Physician Fee Schedule Lookup Tool on the homepage and confirm final pricing guidance through CMS or your local Medicare Administrative Contractor (MAC).

Note: amounts shown are estimates based on CMS national averages for Q3 2026.

0645U Reimbursement Rate History

QuarterQ2 2025Q3 2025Q4 2025Q1 2026Q2 2026Q3 2026
National Average Payment

Historical Medicare Reimbursement

2025 Q12025 Q22025 Q32025 Q42026 Q12026 Q22026 Q3

No published quarterly historical rates are available yet for this code.

QuarterNon-Facility RateFacility RateYoY % Change (Non-Fac)YoY % Change (Fac)
2026 Q3
2026 Q2
2026 Q1
2025 Q4
2025 Q3
2025 Q2
2025 Q1

Q3 2026 Breakdown

ComponentOffice (Non-Fac)Facility (Hosp)
Work RVU
Practice Expense (PE)
Malpractice (MP)
Total RVUs0.000.00

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Compare a payment against the Medicare benchmark for this code.

Medicare rates are used as a benchmark only. Actual payer contracts, modifiers, place of service, units, and billing rules may affect reimbursement. This tool is for educational and operational review purposes, not legal or billing advice.

Commercial Payer Rates for 0645U

Pro Feature

National average reimbursement from major commercial payers based on CMS Transparency in Coverage machine-readable files.

BCBS
$91.46
-4.0% vs Medicare
UnitedHealthcare
$86.29
-9.5% vs Medicare
Aetna
$82.03
-14.0% vs Medicare
Cigna
$121.11
+27.0% vs Medicare
ModifierPlace of ServiceAvg. Ratevs MedicarePercentile Range
NULLOffice (11)$91.46-4.0%$80 — $104
NULLTelehealth (02)$88.20-7.4%$76 — $102
NULLFacility (21)$79.31-15.6%$68 — $95
NULLOutpatient Hospital (22)$84.92-10.2%$71 — $99
NULLHome (12)$96.14+1.0%$84 — $113

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Source: CMS Transparency in Coverage machine-readable files (MRFs). Commercial rates reflect payer-published negotiated amounts and may not reflect individual contracted rates.

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Facility vs. Non-Facility (Office) Payment

Facility vs. non-facility pricing most commonly applies to physician services paid under the RVU-based Physician Fee Schedule. For 0645U (Clinical Laboratory Test), the payment methodology may not include both facility and non-facility rates.

Learn How This Reimbursement Is Calculated

Medicare reimbursement is determined by RVUs, geographic adjustments, and the annual conversion factor.

Frequently Asked Questions

What is the 2026 Medicare rate for 0645U?

Medicare does not publish a single national reimbursement rate for 0645U in 2026 (No National Rate). Use MedFeeSchedule's Medicare Physician Fee Schedule Lookup Tool to explore locality-adjusted estimates when applicable.

What is the description for code 0645U?

Oncology (leukemia), minimal residual disease (mrd) detection for rearrangements, based on digital pcr, blood or bone marrow, reported as not detected or detected with estimated abundance

Why do facility and non-facility payments differ for 0645U?

Facility vs. non-facility differences usually apply to RVU-based physician services. 0645U may not use both facility and non-facility pricing depending on its payment methodology.

How can I find my local Medicare rate for 0645U?

Use MedFeeSchedule's Medicare Physician Fee Schedule Lookup Tool on the homepage to estimate your locality-adjusted reimbursement. Medicare payment can vary based on geographic adjustments (GPCI), place of service, and claim specifics.

Is 0645U covered by Medicare?

Coverage depends on medical necessity, setting, and Medicare policy. Some codes may be bundled, contractor-priced, or restricted. Verify final coverage guidance through CMS or your local MAC when applicable.

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